Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
Human
730 primer pairs across 25 of 25 genes in this pathway.
| Gene | Primer pairs | |
|---|---|---|
| ATM | 40 | View all 40 |
| BARD1 | 50 | View all 50 |
| BLM | 40 | View all 40 |
| BRCA1 | 50 | View all 50 |
| BRCA2 | 10 | View all 10 |
| BRIP1 | 10 | View all 10 |
| DNA2 | 10 | View all 10 |
| EXO1 | 40 | View all 40 |
| KAT5 | 40 | View all 40 |
| MRE11 | 30 | View all 30 |
| NBN | 20 | View all 20 |
| PALB2 | 10 | View all 10 |
| RAD50 | 10 | View all 10 |
| RAD51 | 40 | View all 40 |
| RAD51AP1 | 20 | View all 20 |
| RAD51B | 120 | View all 120 |
| RAD51C | 20 | View all 20 |
| RAD51D | 30 | View all 30 |
| RBBP8 | 30 | View all 30 |
| RMI1 | 50 | View all 50 |
| RMI2 | 10 | View all 10 |
| SEM1 | 10 | View all 10 |
| TOP3A | 20 | View all 20 |
| WRN | 10 | View all 10 |
| XRCC2 | 10 | View all 10 |
Source: R-HSA-9704646 · Pathway data from Reactome, released under CC0.